Lung cancer is a common type of malignancy and has the highest mortality rate among all cancer-related deaths. Metastasis from primary lung cancer can occur to almost any organ, but the most common sites for metastasis include brain, liver, adrenal glands and bones. Metastasis to soft tissues is uncommon and has been rarely reported. In this case report, we describe an unusual presentation of lung cancer in a patient who presented with shortness of breath. He was found to have large pericardial and pleural effusions. An incidental finding of a firm, right-sided, painless subcostal mass was observed. The pericardial fluid showed was found to contain malignant cells and the soft tissue mass was positive for adenocarcinoma of lung origin. A multispecialty approach to the diagnosis and treatment included internal medicine, cardiology, hematology-oncology, cardiothoracic surgery, interventional radiology, and palliative medicine. Treatment included surgical drainage of the pleural and pericardial effusions as well as resection of the chest wall lesion.