Clinical Presentation: A 64-year-old man presented with five days history of fever and respiratory symptoms after which he developed acute progressive ascending lower limb weakness and numbness. He developed these symptoms within a week of testing positive for COVID-19. Nerve conduction study findings were consistent of severe generalized, mixed, mainly axonal sensori-motor poly radiculo-neuropathy. He was treated with intravenous immunoglobulin (IVIG) for a total of five days and showed significant improvement. 

Conclusion: The diagnosis of GBS should be considered in known COVID-19 patients who develop weakness or sensorineural findings during the course of their illness, despite the presence of fever and respiratory symptoms at the onset of neurological symptoms. Though the syndrome is generally considered to be rare, early diagnosis and intervention can significantly improve outcomes and reduce the need of ventilatory support. The strength of the association of COVID-19 and GBS is still unclear but a high index of suspicion should be maintained during this pandemic.