Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder in the US and Europe with an estimated prevalence range of 14-49% in middle aged men. Medical Nutrition Therapy (MNT) is a vital component of the clinical management of OSA, its co-morbidities and its sequelae. As experts in MNT, Registered Dietitian Nutritionists (RDN) are positioned to take a leading role in the treatment of OSA. There is a strong relationship between nutrition, OSA and its milieu, which supports the need to explore and implement therapeutic approaches to treating OSA that include nutrition. Several approaches have shown promise including reduced calorie levels, adjusted macronutrient distribution range and sodium restriction. More research is needed to identify optimal and safe therapeutic approaches to the nutritional management of OSA.