Abstract

Photochemical Screening of Ocimum Santum Leaves and Inorganic Components and Its Effects on Diabetic Rats

Author(s): Shiv Kumar Jayant, Nalini Srivastava

Phytochemical constituents and the hypoglycemic activity of aqueous and ethanolic extracts of Ocimum sanctum was investigated in alloxan induced diabetic rats. Qualitative phytochemical screening of the methanol extracts and paroximate composition, energy, carbohydrates, mineral elements confirmed the presence of leave extract element. Methanol extracts of Ocimum sanctum administered orally at a dose level of 2.5 mg/kg body weight for two weeks showed a significant decrease (p<0.05) in the blood glucose and lipid profile levels of the alloxan induced treated rats when compared with non-treated rats. Methanol extract showed a better hypoglycemic activity and antidiabetic potentials of Ocimum sanctum extracts. Thus, its extract can be further processed for drug development. PDF